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Immune thrombocytopenia associated with pulmonary tuberculosis
Authors:Ahmet Ursavas  Dane Ediger  Rıdvan Ali  Duygu Köprücüoglu  Dilek Bahçetepe  Güzin Kocamaz  Funda Coskun  Ercüment Ege
Institution:1. Centro de Vigilancia Sanitaria Veterinaria VISAVET, Universidad Complutense de Madrid, Avda. Puerta de Hierro s/n, 28040 Madrid, Spain;2. Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad Complutense de Madrid, Avda. Puerta de Hierro s/n, 28040 Madrid, Spain;3. CZ Veterinaria S.A., C/Torneiros s/n, 36410 Porriño, Pontevedra, Spain;4. Subdirección General de Sanidad e Higiene Animal y Trazabilidad, Dirección General de la Producción Agraria, Ministerio de Agricultura y Pesca, Alimentación y Medio Ambiente, Madrid, Spain;5. Servicio de Sanidad Animal, Dirección General de Agricultura y Ganadería, 06800 Mérida, Spain;6. Université Paris-Est, Laboratoire National de Référence Tuberculose, Unité Zoonoses Bactériennes, Laboratoire de Santé Animale, ANSES, Maisons-Alfort, France
Abstract:Many hematological abnormalities, such as pancytopenia, anemia, and leukocytosis, can be associated with tuberculosis (TB). Immune thrombocytopenic purpura (ITP) is an extremely rare event in TB. We report a 46-year-old male patient who was admitted to hospital with a history of weight loss, combined with hemoptysis, fever, cough, sputum, general malaise, and night sweats. Physical examination revealed a body temperature of 38.8°C, and petechiae distributed over the lower extremities. Laboratory findings were as follows: erythrocyte sedimentation rate, 84 mm/h; white blood cells, 7070/mm3; hemoglobin, 11.7 g/dl; and platelet count, 4000/mm3. On Ziehl-Neelsen stain of sputum, acid-fast bacilli were observed. Anti-tuberculosis therapy was started, together with prednisolone, 0.5 mg/kg per day, from the day of admission. He was treated successfully with the steroid and antituberculous drugs.
Keywords:Tuberculosis  Thrombocytopenia  ITP
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