盐酸罗哌卡因加舒芬太尼用于腰硬联合阻滞分娩镇痛的临床研究

目的探究应用盐酸罗哌卡因联合舒芬太尼用于腰硬联合阻滞分娩镇痛的临床效果。方法选自该院2010—2012年收治的足月初产妇共100例,以随机的方式分为对照组与观察组,每组各有产妇50例。对照组产妇不采取任何镇痛方法,为自然分娩,观察组产妇则接受盐酸罗哌卡因加舒芬太尼用于腰硬联合阻滞分娩镇痛方法。对比两组产妇的各项临床指标。结果相对于对照组,观察组产妇失血量、生命体征变化、新生儿Apgar评分以及下肢肌力等无显著差异性,两者对比差异无统计学意义（P〉0.05）;而观察组产妇的血流动力学、镇痛时间影响性以及产程时间等对比于对照组产妇具有显著优越性,两者对比差异有统计学意义（P〈0.05）。两组产妇分娩之后均无出现严重不良反应。结论对足月分娩产妇应用盐酸罗哌卡因加舒芬太尼用于腰硬联合阻滞分娩镇痛,临床效果突出确切,对产妇和新生儿不会产生严重的影响,具有安全高效的优点,值得临床推广。

Clinical Study on the Application of Ropivacaine Hydrochloride Combined with Sufentanil in Combined Spinal Epidural Block Anesthesia for Labor Analgesia

Objective To explore the clinical effect of ropivacaine hydrochloride combined with sufentanil applied to combined spinal epidural block anesthesia on labor analgesia. Methods 100 cases full-term primipara admitted in our hospital from 2010 to2012 were randomly divided into the control group and the observation group with 50 cases in each. The primiparas in the control group were not given any analgesia methods for natural childbirth, while the primiparas in the observation group were given combined spinal epidural block anesthesia for labor analgesia. The clinical indicators of the two groups of primiparas were compared.Results There were no statistically significant differences in maternal blood loss, changes in vital signs, neonatal Apgar score and lower limb muscle strength between the control group and the observation group（P〈0.05）; the hemodynamics, analgesic effect and labor duration of the observation group were much better than those of the control group, the differences between the two groups were statistically significant（P〈0.05）. No severe adverse reactions occurred in both groups of primiparas after delivery. Conclusion Ropivacaine hydrochloride combined with sufentanil applied to combined spinal epidural block anesthesia for the labor analgesia of full-term puerperants is safe and effective, its clinical effect is significant and exact without affecting the puerperants and the neonates severely, and it is worthy of clinical promotion.