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Evaluation of the Xpert® group B streptococcus real-time polymerase chain reaction assay compared to StrepB Carrot Broth™ for the rapid intrapartum detection of group B streptococcus colonization
Authors:Deirdre Leigh Church  Heather Baxter  Tracie Lloyd  Beverley Miller  Daniel B. Gregson
Affiliation:1. Calgary Laboratory Services, Calgary Health Region and the University of Calgary, Calgary, T2L 2K8 Alberta, Canada;2. Department of Pathology and Medicine, Calgary Health Region and the University of Calgary, Calgary, T2L 2K8 Alberta, Canada;3. Department of Medicine, Calgary Health Region and the University of Calgary, Calgary, T2N 2T9 Alberta, Canada;4. Department of Family Medicine, Calgary Health Region and the University of Calgary, Calgary, T2R 0X7 Alberta, Canada
Abstract:Xpert group B streptococcus (GBS) was compared to StrepB Carrot Broth™ (SCB) for the detection of intrapartum GBS colonization by dually collecting vaginal/rectal swabs from 231 women. Xpert GBS detected all of the cases (45, 19.5%), but 4 were missed by SCB. A rapid Xpert GBS service for women in labor would increase costs by ∼$55?000 per annum in our region.
Keywords:Group B streptococcus   Xpert GBS   Strep carrot broth
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