褐藻多糖硫酸酯对老龄小鼠GSH和GR含量的影响 |
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引用本文: | 杨成君,李俐,李晓林,刘昊川. 褐藻多糖硫酸酯对老龄小鼠GSH和GR含量的影响[J]. 中国实验诊断学, 2010, 14(10): 1549-1550 |
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作者姓名: | 杨成君 李俐 李晓林 刘昊川 |
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作者单位: | 1. 吉林大学白求恩医学院生物化学教研室,吉林,长春,130021 2. 吉林大学白求恩医学院生物化学与分子生物学实验中心吉林,长春,130021 3. 吉林大学白求恩医学院临床医学七年制学生,吉林,长春,130021 |
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摘 要: | 目的研究褐藻多糖硫酸酯(APS)对老龄小鼠谷胱甘肽(GSH)和谷胱甘肽还原酶(GR)的影响。方法比色分析法测GR、GSH含量变化。结果褐藻多糖组小鼠脑、心、肾GR含量明显高于对照组(P0.05);褐藻多糖组小鼠脑、心、肾GSH含量明显高于对照组(P0.01)。结论褐藻多糖能提高老龄小鼠机体GR、GSH活力,增强机体抗氧化能力。
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关 键 词: | 褐藻多糖硫酸酯 老龄小鼠 GR GSH |
Effect of algal polysaccharide sulfate on the GSH and GR content of aging mouse |
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Affiliation: | YANG Cheng-jun,LI Li,LI Xiao-lin,et al.(1.Department of Biochemistry;2.Experimental Center of Biochemistry and Molecular Biology,Jilin University,Changchun 130021,China) |
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Abstract: | Objective to study the effect of algal polysaccharide sulfate(APS) on the GSH and GR content of aging mouse.Methods to measure the GR,GSH content with colorimetric analysis.Results GR content in brain,heart and kidney tissues in APS-treatment mouse is higher than that in control(P0.05),GSH content in brain,heart and kidney tissues in APS-treatment mouse is higher than that in control(P0.01).Conclusion APS can enhance the activity of GR and GSH of aging mouse,then increased the antioxidant capability of body. |
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Keywords: | GR GSH |
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