鱼腥草滴眼液联合吡嘧司特钾滴眼液治疗过敏性结膜炎的疗效观察

目的:研究比较鱼腥草滴眼液联合吡嘧司特钾滴眼液治疗过敏性结膜炎的临床疗效。方法:过敏性结膜炎患者63例,随机分为观察组和对照组。对照组31例采用吡嘧司特钾滴眼液,观察组32例采用鱼腥草滴眼液联合吡嘧司特钾滴眼液。治疗前后观察眨眼、眼痒、眼红、异物感等症状,结膜水肿、充血及上、下睑结膜乳头和滤泡等体征,评价治疗有效率。结果:观察组和对照组治疗前症状、体征评分分别为:9.38±0.71和9.41±0.56、10.21±1.03和10.68±0.99,两组差异无统计学意义;观察组和对照组治疗后症状和体征评分分别为:1.22±0.61和4.25±0.84,1.21±0.60和5.78±1.29,两组差异有统计学意义。观察组和对照组治疗后有效率分别为78.12%和32.25%,两组差异有统计学意义。结论:鱼腥草滴眼液联合吡嘧司特钾滴眼液可明显改善过敏性结膜炎患者的临床症状及体征,提高疗效。

Effect of houttuynia cordata eye drops combined with pemirolast potassium eye drops on the treatment of allergic conjunctivitis

AIM: To investigate the clinical effectiveness of houttuynia cordata eye drops combined with pemirolast potassium eye drops on the patients with allergic conjunctivitis.

METHODS: Totally, 63 patients with allergic conjunctivitis were randomly divided into the control group(31 cases)and the observation group(32 cases). The patients in the control group were treated with pemirolast potassium eye drops alone while patients in the observation group were medicated with pemirolast potassium eye drops combined with houttuynia cordata eye drops. Symptoms such as nictation, eye itching, red eye, foreign body sensation and signs such as conjunctival edema and hyperemia, upper and lower palpebral conjunctiva nipple and filtering blebs were observed before and after treatment.

RESULTS: The pretreatment symptom evaluation scored 9.38±0.71 and 9.41±0.56 respectively in the observation group and the control group and their pretreatment sign evaluation scored respectively 10.21±1.03 and 10.68±0.99, with no significant difference between the two groups. After the treatment, symptom evaluation scored 1.22±0.61 and 4.25±0.84 for the observation group and control group respectively and their sign evaluation scored respectively 1.21±0.60 and 5.78±1.29, with statistical difference between the two groups. The effective rate of the observation group(78.12%)was significantly higher than that of the control group(32.25%), and with statistical difference.

CONCLUSION: The pemirolast potassium eye drops combined with houttuynia cordata eye drops can ameliorate the clinical symtoms and signs of the patients with allergic conjunctivitis and improve the treatment efficacy.