| 通络益肾汤对大鼠糖尿病性周围神经病变的治疗作用 |
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| 引用本文： | 赵容杰 金相赞 金梅红 梁在夏 赵正林. 通络益肾汤对大鼠糖尿病性周围神经病变的治疗作用[J]. 延边医学院学报, 2005, 28(3): 163-166 |
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| 作者姓名： | 赵容杰 金相赞 金梅红 梁在夏 赵正林 |
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| 作者单位： | [1]延边大学基础医学院药理学教研室,吉林延吉133000 [2]大邱韩医科大学,韩国 [3]延边大学基础医学院人体解剖学与组织胚胎学教研室,吉林延吉133000 |
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| 摘 要： | [目的]观察通络益肾汤对糖尿病性周围神经病变的治疗效果.[方法]用链脲佐菌素制作大鼠糖尿病模型,12周后糖尿病治疗组大鼠每日灌胃给予通络益肾汤浓缩液78 mL/kg,4周后用电子显微镜观察大鼠坐骨神经的形态学变化.[结果]通络益肾汤对糖尿病周围神经病变大鼠坐骨神经的损伤有明显好转.[结论]通络益肾汤对糖尿病性周围神经病变有治疗作用.
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| 关 键 词： | 糖尿病性神经病 糖尿病,实验性 植物,药用 大鼠 |
| 文章编号： | 1000-1824(2005)03-0163-04 |
| 收稿时间： | 2005-05-12 |
| 修稿时间： | 2005-05-12 |
Therapeutic effects of Tongluoyishentang for diabetic peripheral neuropathy in rats |
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| ZHAO Rong-jie , Kim Sang-chan, JIN Mei-hong, Yang Chae-ha, ZHAO Zheng-lin. Therapeutic effects of Tongluoyishentang for diabetic peripheral neuropathy in rats[J]. Journal of Medical Science Yanbian University, 2005, 28(3): 163-166 |
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| Authors: | ZHAO Rong-jie Kim Sang-chan JIN Mei-hong Yang Chae-ha ZHAO Zheng-lin |
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| Affiliation: | 1. Department of Pharmacology, Yanbian University College of Basic Medicine, Yanji 133000, Jilin China ; 2. Daegu Haany University, South Korea ;3. Department of Human Anatomy and Histology and Embr3ology , Yanbian University College of Basic Medicine, Yanji 133000, Jilin , China |
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| Abstract: | OBJECTIVE To study the therapeutic effects of Tongluoyishentang for diabetic peripheral neuropathy. METHODS The models of diabetes of rats were made by Streptozotocin (STZ). 12 weeks after, rats in diabetic treatment group were given Tongluoyishentang 78.0 mL/kg for 4 weeks. The peripheral neuropathy of rats were observed under transmission electronic microscope. RESULTS The diabetic sciatic neuropathy of rats was significantly improved by Tongluoyishentang. CONCLUSION Tongluoyishentang has therapeutic effects for diabetic peripheral neuropathy. |
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| Keywords: | diabetic neuropathies diabetes mellitus, experimental plants, medicinal rats |
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