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FLEEOX新辅助化疗对进展期胃癌患者术后并发症的影响
引用本文:张才华,范朝刚,李国立,曹建民,许健,李宁,黎介寿.FLEEOX新辅助化疗对进展期胃癌患者术后并发症的影响[J].医学研究生学报,2011,24(11):1158-1161.
作者姓名:张才华  范朝刚  李国立  曹建民  许健  李宁  黎介寿
作者单位:1. 南京大学医学院临床学院(南京军区南京总医院)解放军普通外科研究所,南京,210002
2. 南京大学医学院临床学院(南京军区南京总医院)医学影像科,南京,210002
基金项目:南京军区重点课题(08Z028)
摘    要:目的新辅助化疗可改善胃癌患者预后,文中研究FLEEOX新辅助化疗对进展期胃癌患者术后并发症的影响。方法 41例经CT评价为不可切除的进展期胃癌患者作为实验组,接受2个疗程的FLEEOX新辅助化疗后再行手术治疗,同期54例进展期胃癌患者作为对照组接受单纯手术治疗,术后观察2组患者术后并发症发生率的差别。结果 2组患者的术后并发症总体发生率为17.9%,其中FLEEOX组为17.1%,对照组为18.5%。2组无明显差异(P=0.85)。结论进展期胃癌患者接受FLEEOX方案新辅助化疗后并未增加术后并发症的风险,是安全可行的。

关 键 词:胃癌  新辅助化疗  术后并发症

Neoadjuvant FLEEOX chemotherapy and post-operative complications of advanced gastric cancer
ZHANG Cai-hua,FAN Chao-gang,LI Guo-li,CAO Jian-min,XU Jian,LI Ning,LI Jie-shou.Neoadjuvant FLEEOX chemotherapy and post-operative complications of advanced gastric cancer[J].Bulletin of Medical Postgraduate,2011,24(11):1158-1161.
Authors:ZHANG Cai-hua  FAN Chao-gang  LI Guo-li  CAO Jian-min  XU Jian  LI Ning  LI Jie-shou
Institution:ZHANG Cai-hua1,FAN Chao-gang1,LI Guo-li1,CAO Jian-min2,XU Jian2,LI Ning1,LI Jie-shou1(1.PLA Research Institute of General Surgery,2.Department of Medical Imaging,School of Medicine,Nanjing University/Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China)
Abstract:] Objective Neoadjuvant chemotherapy plays an important role in the treatment of gastric cancer.Clinical studies have shown that neoadjuvant chemotherapy improves the prognosis of gastric cancer.This article evaluates effects of neoadjuvant FLEEOX chemotherapy on post-operative complications in patients with advanced gastric cancer.Methods Forty-one advanced gastric cancer patients considered unresectable by CT evaluation(experimental group) were treated with two cycles of neoadjuvant FLEEOX chemotherapy fo...
Keywords:Gastric cancer  Neoadjuvant chemotherapy  Postoperative complication  
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