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Perioperative management of the patient with chronic kidney disease
Authors:Mark DoughertyStephen T. Webb
Affiliation:Mark Dougherty MB BCh BAO MRCP FCARCSI is a Specialist Registrar in Anaesthesia at The Royal Hospitals, Belfast, UK. Conflicts of interest: none declared; Stephen T Webb MB BCh BAO FRCA EDIC is a Consultant in Anaesthesia & Intensive Care Medicine at Papworth Hospital, Cambridge, UK. Conflicts of interest: none declared
Abstract:The prevalence of chronic kidney disease (CKD) is increasing. Perioperative management of patients with CKD aims to control modifiable risk factors associated with acute kidney injury (AKI). AKI on the background of CKD may lead to dialysis dependency. CKD has widespread cardiovascular, endocrine, metabolic and haematological effects. Preoperative assessment and preparation require multidisciplinary input from the surgical, anaesthetic and nephrology teams. Perioperative care should ensure the correction of hypovolaemia, maintenance of renal blood flow and perfusion pressure, prevention of radiocontrast-induced nephrotoxicity, avoidance of nephrotoxic drugs and treatment of urinary tract obstruction.
Keywords:Acute kidney injury   chronic kidney disease   nephrotoxicity   renal blood flow
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