Detection of a porcine rotavirus strain with VP4, VP7 and NSP4 genes of different animal origins |
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Authors: | Jianzhong Yi Chenqian Liu |
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Institution: | (1) Institute of Animal Husbandry Veterinary Sciences, Shanghai Academy of Agricultural Sciences, 2901 Beidi Road, Shanghai, 201106, China |
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Abstract: | A new rotavirus strain, sh0902, was detected in diarrheic piglets on a farm in Shanghai, China, and its genotype was characterized
as G1P7]. Analysis of the VP4, VP7 and NSP4 genes demonstrated VP4 homology to bovine and swine rotavirus strains; the nucleotide
(nt) and amino acid (aa) identities were 99.7% and 99.5%, respectively. The VP7 gene was highly homologous to that of a giant
panda rotavirus strain, with 98.5% similarity at the nt level and 99% similarity at the aa level. The nucleotide sequence
of the NSP4 gene displayed high homology to human rotavirus strain R479, with 99.7% identity at the nt level and 99.3% identity
at the aa level. This is the first report of an unusual porcine rotavirus strain with VP4, VP7 and NSP4 genes that are highly
homologous to bovine, swine, giant panda and human strains isolated at geographically distant sites (South Korea, China and
India). Our data indicate that rotaviruses have circulated among humans and animals and undergone genome reassortment. |
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