Identification of human papillomavirus types in oral verruca vulgaris |
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Authors: | K. Adler-Storthz J. R. Newland B. A. Tessin W. A. Yeudall E. J. Shillitoe |
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Affiliation: | Departments of Microbiology, University of Texas Dental Branch, Houston;Pathology and Radiology, University of Texas Dental Branch, Houston;Department of Oral Medicine and Pathology3, Glasgow Dental Hospital, Scotland |
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Abstract: | Abstract Eleven oral verruca vulgaris specimens were examined for the presence of papillomavirus structural antigens by reaction with antibody to type-common antigens and detection by the avidin-biotin-peroxidase complex method. The specimens were also examined by in situ hybridization with biotin-labelled human papillomavirus (HPV) DNA to determine the specific HPV types present in the lesions. Six of the 11 specimens were positive for papillomavirus structural antigens. Of these 6, 5 hybridized to the HPV Type 2 (HPV2) probe and one to the HPV4 probe. |
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