Signet-ring cell carcinoid of the gallbladder |
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| Authors: | M. PAPOTTI D. GALLIANO G. MONGA |
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| Affiliation: | Department of Biomedical Sciences and Human Oncology, University of Turin, Italy. |
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| Abstract: | A case of signet-ring cell carcinoid of the gallbladder is reported. The tumour diffusely infiltrated the gallbladder wall and extensively ulcerated the mucosa. Neoplastic nests were composed of numerous signet-ring cells mixed with clear endocrine cells. The latter expressed chromogranin A, gastrin and somatostatin and contained neurosecretory granules. The diagnostic problem of differentiating between signet-ring cell carcinomas and composite adenocarcinoma-carcinoid tumours is discussed. |
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| Keywords: | gallbladder signet-ring cells neuroendocrine carcinoid |
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