| 钙敏感受体及其相关信号转导通路对细胞因子分泌的调控 |
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| 引用本文： | 吴秋月,孙轶华.钙敏感受体及其相关信号转导通路对细胞因子分泌的调控[J].检验医学,2014(5):564-569. |
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| 作者姓名： | 吴秋月 孙轶华 |
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| 作者单位： | 哈尔滨医科大学附属第二医院检验科,黑龙江哈尔滨150081 |
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| 基金项目： | 国家自然科学基金资助项目（81101315、81371892） |
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| 摘 要： | 本文对钙敏感受体(CaSR)的结构特点、信号转导、生理作用进行了概述。重点阐述了CaSR介导的相关信号转导通路对细胞因子分泌的调控机制,并对二者关系的研究前景进行了展望。
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| 关 键 词： | 钙敏感受体 细胞因子 核转录因子通路 丝裂原活化蛋白激酶通路 |
Calcium sensing receptor and regulation of related signal transduction pathways on the secretion of cytokine |
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| WU Qiuyue,SUN Yihua.Calcium sensing receptor and regulation of related signal transduction pathways on the secretion of cytokine[J].Laboratory Medicine,2014(5):564-569. |
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| Authors: | WU Qiuyue SUN Yihua |
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| Institution: | ( Department of Clinical Laboratory, the Second Affiliated Hospital of Harbin Medical University, Heilongjiang Harbin 150081, China) |
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| Abstract: | In this article,we summary the calcium sensing receptor（CaSR）structure,signal transduction and physiological function.The regulation mechanism of CaSR on the secretion of cytokines was described through the related signal transduction pathways,and we prospect the relations between them. |
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