白念珠菌对唑类药物耐药机制中生物膜作用的研究进展 |
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引用本文: | 史册,;刘锦燕,;魏冰,;项明洁. 白念珠菌对唑类药物耐药机制中生物膜作用的研究进展[J]. 检验医学, 2014, 0(6): 692-694 |
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作者姓名: | 史册, 刘锦燕, 魏冰, 项明洁 |
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作者单位: | [1]上海交通大学医学院附属瑞金医院检验科,上海200025; [2]上海交通大学医学院附属瑞金医院卢湾分院放免检验科,上海200020 |
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基金项目: | 基金项目:上海市科委基金资助项目(114119b0500);上海市卫生局基金资助项目(2009239) |
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摘 要: | 白念珠菌是人体最常见的机会性致病真菌。唑类药物广泛应用于临床以对抗白念珠菌感染,但白念珠菌对唑类药物的耐药现象越来越严重,作为其耐药机制的一个方面,生物膜的作用备受关注。我们主要介绍生物膜相关的研究进展。
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关 键 词: | 白念珠菌 唑类药物 耐药机制 生物膜 |
The research advance of biofilm in the mechanisms of azole resistance to Candida albicans |
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Affiliation: | Sill Ce , LIU Jinyan, WEI Bing , XIANG Mingjie ( 1. Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; 2. Radioimmunology and Clinical Laboratory, Luwan Branch, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200020, China) |
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Abstract: | Candida albicans is the most important opportunistic fungus.As the first choice to treat the infection, azole is widely used,but the resistance to azole is more and more common.In the lately years,researchers have focused on the mechanism of azole resistance and biofilm formation.This review summarizes the research advance of biofilm. |
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Keywords: | Candida albicans Azole Resistance mechanism Biofilm |
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