| 绞股蓝多糖抗肿瘤作用及其对荷瘤动物免疫机能的影响 |
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| 引用本文： | 唐晓玲,王佾先,亢寿海,钱新华. 绞股蓝多糖抗肿瘤作用及其对荷瘤动物免疫机能的影响[J]. 药学与临床研究, 1999, 7(1): 15-17 |
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| 作者姓名： | 唐晓玲 王佾先 亢寿海 钱新华 |
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| 作者单位： | 南京医科大学第一附属医院，江苏省肿瘤研究所，江苏省肿瘤研究所，江苏省肿瘤研究所 南京 210029，南京 210009，南京 210009，南京 210009 |
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| 基金项目： | 1997年江苏省中医管理局科研基金 |
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| 摘 要： | 从江苏地区产的绞股蓝中提取的多糖成分进行了药理试验。结果表明,绞股蓝多糖对小白鼠移植性肿瘤S_(180)有显著的抑制作用;用绞股蓝多糖无任何毒副作用,且能对抗化疗药引起的骨髓抑制等不良反应;保护细胞免受自由基的攻击,对机体的免疫机能有一定的增强作用。
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| 关 键 词： | 绞股蓝 多糖 抗肿瘤 免疫机能增强 |
| 收稿时间： | 1998-03-30 |
Gynostemma pentaphyllum Makino Polysaccharide Anti-tumor Effect and Immunological Influence in Transplanted S180 Mouse |
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| Tang Xiaoling,Wang Yixian,Kang Shouhai and Qian Xinhua. Gynostemma pentaphyllum Makino Polysaccharide Anti-tumor Effect and Immunological Influence in Transplanted S180 Mouse[J]. Pharmacertical and Clinical Research, 1999, 7(1): 15-17 |
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| Authors: | Tang Xiaoling Wang Yixian Kang Shouhai Qian Xinhua |
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| Affiliation: | Tang Xiaoling First Affiliated Hospital of Nanjing Medical University (Nanjing 210029) Wang Yixian Kang Shouhai Qian Xinhua Jiangsu Provincial Institute of Tumor (Nanjing 210009) |
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| Abstract: | This study was designed to investigate pharmacological effects of Gynostemma pentaphyllum Polysaccharide (GPP)extracted from Gynostemma pentaphyllum Makino which was collected in Jiangsu province. The results showed significant suppressive effects of transplanted S180 tumor growth in mouse by both GPP ig and ip. There were no any toxic or side effects of GPP during the therapy. In addition, GPP also demonstrated the significant effects in improvement of bone marrow suppression induced by chemotherapy protection from free radical attack on cells,and enhancement of immunologic functions. |
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| Keywords: | Gynostemma pentaphyllum Makino Polysaccharide Anti-tumor Immunological enhancement |
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