宫颈癌的术后放化疗

 宫颈癌术后有高危因素患者易局部复发。已经证实有高危因素患者术后行辅助放疗能提高局部控制率，但不能提高总生存率。有研究显示同步放化疗较单纯放疗能提高生存率，但血液及消化系统不良反应较重。调强放疗（IMRT）能提高靶区适形度及剂量，同时降低周围正常组织剂量，IMRT有较好的局部控制率及生存率。

Postoperative radiotherapy and chemotherapy in cervical cancer

Local recurrence is more frequent in postoperative cervical cancer patients with high-risk factors. It is confirmed that adjuvant pelvic radiotherapy (RT) for the cervical cancer patients after surgery with high-risk factors can improve local control but can′t improve the overall survival. Researches show that concurrent chemo-radiotherapy (CCRT) can improve survival rates compared with radiotherapy, but the adverse effects such as leucopenia and gastrointestinal toxicity are observed frequently. Intensity-modulated radiation therapy (IMRT) has been developed to deliver a high radiation dose to an irregular target volume, with relative sparing of adjacent normal tissues. IMRT has excellent local tumor control and overall survival.