A new sesquiterpene lactone glucoside with inhibitory effect on K562 cells from Ixeris sonchifolia (Bge) Hance |
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| Authors: | He W-F Xu B-B Pan J-C Lu J-C Song S-J Xu S-X |
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| Institution: |
a School of Pharmacy, Wenzhou Medical College, Wenzhou, China
b School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China |
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| Abstract: | A new minor sesquiterpene lactone glucoside, ixerin ZA (1), together with 16 known compounds, were isolated from the whole plants of Ixeris sonchifolia (Bge) Hance. The structure of 1 was elucidated as 1(10),3,11(13)-guaiatriene-12,6-olide-2-one-3-O-6'-(p-metheoxyphenylacetyl)]-β-glucopyranoside on the basis of spectroscopic and chemical evidence. Compound 1 exhibited an inhibitory effect on K562 cells. |
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| Keywords: | Ixeris sonchifolia Compositae Ixerin ZA K562 cells |
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