| 基质金属蛋白酶和肿瘤血管生成拟态的相关研究 |
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| 引用本文： | 林俊豪,冯思同,栗枭杰,安海燕.基质金属蛋白酶和肿瘤血管生成拟态的相关研究[J].现代肿瘤医学,2017(3):470-473. |
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| 作者姓名： | 林俊豪 冯思同 栗枭杰 安海燕 |
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| 作者单位： | 南方医科大学,广东 广州,510515 |
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| 基金项目： | 国家自然科学基金青年科学基金(编号81603427) |
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| 摘 要： | 血管生成拟态（vasculogenic mimicry，VM）是一种新的肿瘤细胞血液供应的方式。现有研究表明，基质金属蛋白酶（matrix metalloproteinase，MMPs）具有促进 VM 管道形成的作用。本文将对 MMPs 与血管生成拟态（vasculogenic mimicry，VM）的关系及其相关分子机制进行归纳，进一步探索两者之间的关系，从而为研究 VM 管道形成提供新的思路。
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| 关 键 词： | 基质金属蛋白酶 肿瘤 血管生成拟态 |
Relavent research of matrix metalloproteinases and vasculogenic mimicry |
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| Lin Junhao,Feng Sitong,Li Xiaojie,An Haiyan.Relavent research of matrix metalloproteinases and vasculogenic mimicry[J].Journal of Modern Oncology,2017(3):470-473. |
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| Authors: | Lin Junhao Feng Sitong Li Xiaojie An Haiyan |
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| Abstract: | vasculogenic mimicry(VM)was a new way of the blood supply to the tumor cells. Current research indi-cates that matrix metalloproteinases(MMPs)had roles in promoting the formation of VM pipeline. This paper summa-rized the relationship and the related molecular mechanism between matrix metalloproteinases and vasculogenic mim-icry. We'd like to further explore the relationship between the two mdeanism,so as to provide a new idea for the study of the formation of VM pipeline. |
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| Keywords: | matrix metalloproteinase tumor vasculogenic mimicry |
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