磁共振扩散加权成像参数与宫颈癌组织学特点的相关性

目的:探讨与研究磁共振(MR)扩散加权成像(DWI)参数与宫颈癌组织学特点的相关性.方法:采用回顾性研究方法,2012年9月到2016年1月选择在我院住院诊治的宫颈癌病例84例作为观察组,同期选择由于其他原因进行宫颈检查的女性患者84例作为对照组,两组都给予常规MRI平扫及DWI检查,记录与调查宫颈癌组织学特点与DWI 参数 ADC值,同时进行相关性分析.结果:两组MRI影像学图像均满足诊断及测量要求,未见明显伪影和变形;观察组在T1WI上呈等信号,在T2WI上呈稍高或高信号,DWI上表现为边界清晰的高信号肿块.当MRI DWI b值为1 000 s/mm2时,观察组与对照组的ADC值分别为(0.89±0.15)×10-3mm2/s和(1.50±0.23)×10-3mm2/s,观察组明显少于对照组(P<0.05).ADC值在宫颈癌患者的不同临床分期、淋巴结转移和分化程度中对比都有统计学意义(P<0.05);Pearson相关系数显示宫颈癌患者的ADC值与临床分期、淋巴结转移与分化程度也呈现明显负相关性(P<0.05).结论:MRI诊断宫颈癌有很好的成像质量,且 DWI成像参数ADC值明显降低,与宫颈癌的组织学特点有很好的相关性,能有效反映宫颈癌的病变状况.

Correlation between parameters of magnetic resonance diffusion weighted imaging and histological features of cervical carcinoma

Objective:To study the correlation between the parameters of magnetic resonance (MR) diffusion weighted imaging (DWI) and the histological features of cervical cancer.Methods:Used a retrospective study,84 cases of cervical cancer in our hospital treated from September 2012 to January 2016 were selected.84 cases of female patients with cervical examination at the the same period due to other causes were selected as the control group.Two groups were given conventional MRI and DWI examination.The hematology and DWI ADC parameters were given record with investigation and correlation analysis.Results:Two groups of MRI images met the diagnosis and measurement requirements and there were not obvious artifacts and deformation.The T1WI in the observation group showed equal signal,the T2WI with high or slightly high signal.DWI showed clear boundary hyperintense mass.When the MRI DWI b value was 1 000 s/mm2,the ADC values of the observation group and the control group were (0.89±0.15)×10-3mm2/s and (1.50±0.23)×10-3mm2/s,and the observation group was significantly less than that of the control group (P<0.05).The ADC values in cervical cancer patients with different clinical stages,lymph node metastasis and differentiation were statistically significant (P<0.05).Pearson correlation coefficients showed ADC value with cervical cancer patients showed significant negative correlation with the clinical staging,lymph node metastasis and differentiation degree (P<0.05).Conclusion:MRI diagnosis of cervical cancer has a good imaging quality,and DWI imaging parameters ADC value is significantly reduced and has good correlation with the histological characteristics of cervical cancer,which can effectively reflect the pathological changes of cervical cancer.