射频加热联合放疗治疗颈部淋巴结转移癌

目的:观察射频加热联合放疗治疗颈部淋巴结转移癌的临床疗效,以期为此类患者的诊疗提供参考.方法:分析2015年至2016年在我院接受治疗的颈部淋巴结转移癌患者的临床资料.依据治疗方案不同将患者分为观察组(射频热疗+放疗)41例及对照组(放疗)40例.对比两组短期治疗有效率、肿瘤标志物改变及治疗后复发情况.结果:观察组患者治疗有效率显著高于对照组患者(χ2=4.313,P=0.038).治疗后,两组患者外周血CEA、CYFRA21-1及SCC-Ag水平均显著降低(P<0.05),但观察组患者低于对照组(P<0.05).观察组患者治疗后6个月颈部淋巴结转移癌复发率显著低于对照组(4.88%,2/41 vs 19.44%,7/36;Log-rank χ2=3.995,P=0.046).结论:在颈部淋巴结转移癌的放射治疗中,联合使用射频加热治疗可显著提高疗效,值得临床推广.

Radio-frequency heating therapy combined with radiotherapy in the treatment of cervical metastatic carcinomas

Objective:To analyze the clinical efficacy of radio-frequency heating therapy combined with local radiotherapy in the treatment of cervical metastatic carcinomas.Methods:Clinical data of patients with cervical metastatic carcinomas received treatment at our hospital from 2015 to 2016 were analyzed.Patients were divided into two groups by different therapies,including obseravation group(radio-frequency heating therapy combined with radiotherapy)and control group(radiotherapy).A total of 81 patients were analyzed,observation group with 41 cases,cantrol group with 40 cases.Results:Patients in observation group had higher therapeutic response rate than that of control group,the difference was statistically significant(χ2=4.313,P=0.03).After treatment,both of the two groups got significantly decreased in CEA,CYFRA21-1 and SCC-Ag(P<0.05),but these index were lower in observation group than these of control (P<0.05).Patients in observation group had lower recurrence rate after treatment about 6 months than that of control,the difference was statistically significant(4.88%,2/41 vs 19.44%,7/36;Log-rank χ2=3.995,P=0.046).Conclusion:In the treatment of cervical metastatic carcinomas,radio-frequency heating therapy combined with radiotherapy can significantly improve the clinical efficacy.