比浊法自动测定可利霉素片的效价 |
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引用本文: | 潘强,徐秋阳,潘智鹏,王洋.比浊法自动测定可利霉素片的效价[J].中国药品标准,2012,13(5):354-357. |
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作者姓名: | 潘强 徐秋阳 潘智鹏 王洋 |
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作者单位: | [1]辽宁省食品药品检验所,沈阳110023 [2]辽宁省肿瘤医院,沈阳110006 |
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摘 要: | 目的:建立比浊法测定可利霉素片效价的方法。方法:以金黄色葡萄球菌为试验菌,加菌量为0.5%(V/V),温度为(37±0.5)℃,培养时间3.5~4.0h测定。结果:抗生素线性最佳浓度范围为6.4~15.7 u.mL-1,平均回收率为100.7%(n=9),RSD=1.7%。结论:本方法灵敏、快速、实用,可作为测定可利霉素片效价的方法。
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关 键 词: | 效价 比浊法 可利霉素片 |
Determination of Kelimycin Tablets by Turbidimetric Method |
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Authors: | Pan Qiang Xu Qiuyang Pan Zhipeng and Wan Yang |
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Institution: | Pan Qiang Xu Qiuyang Pan Zhipeng, Wan , Yang ( 1. Liaoning Institute for Food and Drug Control , Shenyang 110023 ; 2. Liaon- ing Provincial Tumor Hospital, Shenyang 110006 ) |
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Abstract: | Objective:To establish a turbidimetric method for the determination of Kelimycin Tablets. Method:The test organism was Staphylococcus aureus . The amount of adding bacteria was 0. 5 % ( V / V ) , incubation time was 3.5 to 4. Oh at 37 ℃ ± 0. 5 ℃. Results: The linearity was in the range of 6. 4to15.7 u. m L-1 and the average recovery was 100. 7% (n =9) ;RSD = 1.7%. Conclusion: The method was sensitive, rapid and feasible for the determination of Kelimycin Tablets. |
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Keywords: | potency turbidimetric method Kelimycin Tablets |
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