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Sclerotic bone metastases from sarcomatoid renal cell carcinoma
Authors:P T Liu  Christopher R Conley  Matthew R Callstrom
Institution:(1) Department of Diagnostic Radiology, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA, US;(2) Department of Pathology, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA, US;(3) Department of Diagnostic Radiology, Mayo Clinic Rochester, Rochester, Minnesota, USA, US
Abstract:We present a case of sarcomatoid renal cell carcinoma with multiple sclerotic skeletal metastatic lesions. Renal cell carcinoma is frequently metastatic at presentation, with a high incidence of skeletal involvement, classically described as osteolytic. However, sclerotic or osteoblastic metastatic skeletal lesions from renal cell carcinoma are rare, with only two previous reports identified in the literature, neither of which involved the sarcomatoid variant of renal cell carcinoma. In our case the sclerotic metastases were characterized by bone scan, computed tomography (CT), magnetic resonance imaging (MRI), and histologic analysis. Received: 8 April 1999 Revision requested: 27 May 1999 Revision received: 24 June 1999 Accepted: 29 June 1999
Keywords:  Sarcomatoid renal cell carcinoma  Bone metastasis  Radiography
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