妊娠妇女不同孕期血清叶酸、维生素B12和铁蛋白检测及其临床意义

目的：通过在不同孕期对妊娠妇女的血清叶酸、维生素B12和血清铁蛋白进行联合检测，为临床上治疗妊娠贫血提供有效依据。方法：对2013年4月~2013年11月期间，在我院待产的1067例妊娠妇女定为观察组，选取107例非妊娠妇女为对照组进行对比试验，分别进行血清叶酸、维生素B12和血清铁蛋白的含量分析，采用化学发光法检测对比两者间含量的差别。结果：随着孕期的增加，血清叶酸、维生素B。和血清铁蛋白的含量呈降低趋势，早孕期妇女的维生素B12与对照组相比无明显差异（P〉0．05），血清叶酸和血清铁蛋白较对照组低，且差异有统计学意义（P〈0．05）；中、晚孕期妇女血清叶酸、维生素B12和血清铁蛋白的含量均低于对照组，差异有统计学意义（P〈0．05）。结论：对不同妊娠期的妇女进行血清叶酸、维生素B12和血清铁蛋白的含量检测，可对妊娠妇女的贫血原因进行准确分析，达到对妊娠妇女的贫血症状进行有效预防和治疗的目的，对胎儿的正常发育也有一定的临床意义。

Serum folic acid,vitamin B12 and ferritin detection of pregnant women in different pregnancy and its clinical significance

Objective ： Through different pregnancy in pregnant women serum folic acid, vitamin B12 and serum ferritin were joint detection, for the clinical treatment of anemia in pregnancy provides effective basis. Methods ： Using chemiluminescence method, the pregnant women and non pregnant women were divided into treatment group and control group, analysis of the serum folic acid, vitamin B12 and serum ferritin in contrast difference.Results With the increase of the content of serum during pregnancy, folic acid, vitamin B12 and serum ferritin decreased, no significant difference compared with the control group of vitamin B12 in early pregnancy women, serum folate and serum ferritin was lower than that in control group, and the difference was statistically significant; in late pregnancy women, serum folic acid, vitamin B12 and serum ferritin were lower than the control group, the difference has statistical significance. Conclusions ： Determination of serum folic acid, to different women during pregnancy vitamin B12 and serum ferritin, can carry out accurate analysis of the causes of anemia in pregnant women, achieving the effective prevention and treatment of anemia of pregnant women＇s objective, also has certain clinical significance for the normal development of the fetus.