139株嗜麦芽寡养单胞菌的临床分布及耐药性分析

目的了解嗜麦芽寡养单胞菌的标本来源、临床分布及耐药状况。方法细菌培养和鉴定严格按照《全国临床检验操作规程》进行;检测139株嗜麦芽寡养单胞菌对临床常用18种抗菌药物的敏感性。结果嗜麦芽寡养单胞菌主要来源于痰标本,占41.01%(57/139);科室分布主要分离自重症监护室(ICU)(33.09%,46/139)和呼吸内科(27.34%,38/139)。该菌对米诺环素、复方新诺明、左氧氟沙星的耐药率较低,分别为15.11%、16.55%、19.42%,对其他抗菌药物的耐药率较高。结论嗜麦芽寡养单胞菌具有高度和多重耐药性,临床抗感染治疗应根据药敏试验结果选用敏感药物。

Analysis of the clinical distribution of 139 strains of stenotrophomonas maltophilia and their drug resistance

Objective To study the chinical distribution of stenotrophomonas maltophilia（SMA）and its drug resistance.Methods 139 strains of SM were cultured and identified by means of the Operation Rules in Nationalwide Clinical Laboratory.Susceptibility of SM to 18 chinical antibiotics commonly used in clinic was detected.Results Sputum was the main resource of SM specimens,accounting for 41.01%（57/139）,isolated mainly from ICU（33.09%,46/139）and Department of Respiratory Medicine（27.34%,38/139）.Its resistance to minocycline,sulphamethoxazole/trimethoprim,and levofloxacin was relatively low（15.11%,16.55% and 19.42% respectively）,but higher to other antimicrobial agents.Conclusion SMA is of a high and multiple drug resistance.So drugs should be chosen based on sensitivity test results in chinical anti-infection therapy.