Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment. |
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| Authors: | M Meradji V H de Villeneuve J Huber W C de Bruijn R G Pearse |
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| Affiliation: | 1. Department of Pediatric Radiology, Erasmus University, Sophia Children''s Hospital and Neonatal Unit, Rotterdam, The Netherlands;2. Department of Pediatrics, Erasmus University, Sophia Children''s Hospital and Neonatal Unit, Rotterdam, The Netherlands;3. Department of Clinical Pathology, Erasmus University, Sophia Children''s Hospital and Neonatal Unit, Rotterdam, The Netherlands |
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| Abstract: | Idiopathic infantile arterial calcification is a disorder of unknown etiology manifested by widespread arterial calcification. This usually leads to early death from coronary artery occlusion. In 12 of the 75 cases in the literature, radiographs were taken and it was possible to make the diagnosis in them all. We present two patients, siblings, in whom the diagnosis was established radiologically. The nature of the calcium deposits was studied in one of the infants and proved to be calcium hydroxyapatite. Therapy with diphosphonate was apparently successful in the other child. |
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| Keywords: | Reprint address: Department of Pediatric Radiology Sophia Children's Hospital Rotterdam The Netherlands |
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