Oral supplements in atopic dermatitis |
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| Institution: | 1. Show Chwan Memorial Hospital, Changhua, Taiwan;2. Division of Plastic Surgery, Changhua Show Chwan Memorial Hospital, Changhua, Taiwan;3. Taiwan Agricultural Chemicals and Toxic Substances Research Institute, Council of Agriculture, Taichung, Taiwan;4. Department of Medical Research, Research Assistant Center, Show Chwan Memorial Hospital, Changhua, Taiwan;1. Independent Medical Sociology Unit, Medical University of Lublin, Lublin, Poland;2. Department of Public Commercial Law, University of Bialystok, Bialystok, Poland;3. Department of Ethics and Human Philosophy, Medical University of Lublin, Lublin, Poland;4. Chair and Department of Trauma Surgery and Emergency Medicine, Medical University of Lublin, Lublin, Poland;5. Chair of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland;1. Departments of Dermatology and Pediatrics, Mt Sinai Health Systems, New York, New York, USA;2. Departments of Dermatology, Preventive Medicine, and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA;1. Laboratório de Pesquisa em Farmacologia Bioquímica - LaFarBio - Grupo de Pesquisa em Neurobiotecnologia, CCQFA - Universidade Federal de Pelotas, UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil;2. Laboratório de Tecnologia e Desenvolvimento de Compósitos e Materiais Poliméricos (LaCoPol), Centro de Ciências Químicas, Farmacêuticas e de Alimentos, Universidade Federal de Pelotas (UFPel), 96010-900 Pelotas, RS, Brazil;3. Laboratório de Síntese Orgânica Limpa - LASOL – CCQFA, Universidade Federal de Pelotas, UFPel, P.O. Box 354, 96010-900 Pelotas, RS, Brazil |
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| Abstract: | Atopic dermatitis (AD) is the most common chronic inflammatory skin disorder. The disease is typified by chronic pruritus, a series of signs and symptoms associated with immune dysfunction (eg, increased immunoglobulin E mediated allergies), and abnormal skin barrier dysfunction (eg, increased response to irritants). Due to the chronic itch and reactivity, patients and parents of affected children will seek therapy. Therapies range from emollients to topical medicaments, including topical corticosteroids, and immunosuppressive agents. Due to concerns about the side effects of the available agents, patients and their loved ones will often seek “natural” agents as therapy. Oral agents that have been tried in (AD) include probiotics, vitamins, oils, and such traditional therapeutics as Chinese herbals and Ayurvedic agents. At this time probiotics may be promising, but there are inadequate data to determine their efficacy. In addition, there are significant concerns for the risks associated with Chinese herbals, which may be associated with liver failure and death, and Ayurvedic agents, which may be tainted with heavy metals. The safest and most effective natural agents are topically applied emollients. |
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