CRP monitoring in fractured neck of femur. A waste of resource? |
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| Institution: | 1. Flinders Medical Centre, Flinders Drive, Bedford Park, SA5042, Australia;2. Flinders University, Flinders Drive, Bedford Park, SA, 5042, Australia;3. University of Amsterdam, 1012 XW, Amsterdam, The Netherlands;1. Southmead Hospital, Bristol, UK;2. University Hospital Coventry and Warwickshire, Coventry, UK;3. Oxford University Hospitals, Oxford, UK;4. Sheffield Northern General Hospital, Sheffield, UK;5. University of the West of England, Bristol, UK;1. Department of Oral and Maxillofacial Surgery, Hamadan University of Medical Sciences, Hamadan, Iran;2. Dental Research Center, Hamadan University of Medical Sciences, Hamadan, Iran;3. Department of Oral and Maxillofacial Radiology, Hamadan University of Medical Sciences, Hamadan, Iran;4. Faculty of Dentistry, Hamadan University of Medical sciences, Hamadan, Iran;5. Department of Biostatistics and Epidemiology, Hamadan University of medical sciences, Hamadan, Iran;1. KU Leuven – University of Leuven, Faculty of Medicine, B-3000 Leuven, Belgium;2. University Hospitals Leuven, Department of Trauma Surgery, B-3000 Leuven, Belgium;3. KU Leuven – University of Leuven, Department of Development and Regeneration, B-3000 Leuven, Belgium;1. Department of Occupational Therapy and Physiotherapy, Aalborg University Hospital, Aalborg, Denmark;2. Department of Orthopaedic Surgery, Aalborg University Hospital, Aalborg, Denmark;1. Orthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People’s Republic of China;2. Department of Traumatic Orthopaedics, Tianjin Hospital, Tianjin, 300211, People’s Republic of China |
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| Abstract: | AimWe aim to assess post-operative CRP serum values in a cohort of patients who underwent surgical treatment for neck of femur fracture (NOF#), and whether CRP is a valid tool for the assessment of these patients post-operatively.Study Design and MethodsRetrospective analysis was carried out on all NOF#'s admitted for surgical fixation between August 2015 and July 2016 in a district general hospital. Primary analysis included serum CRP levels until day 7 post-operatively, with secondary analysis of any documented evidence of post-operative complications (medical and surgical) within 30 days post-operatively.ResultsA total of 365 patients were surgically treated for NOF#’s over the study period. CRP serum levels peaked over the first two days post-operatively to median (IQ range) of 226 mg/L (158–299 mg/L), decreasing to 67 mg/L (45.5–104 mg/L) by day 7 post-operatively. 116 patients had documented post-operative complications within 30 daysof operation. CRP levels in patients with and without complications showed no statistical significance in day-1, day-2 and day-3 post-operatively. However, a significant difference was demonstrated on day-4 (p = 0.017), day-5 (p = 0.003), day-6 (p = 0.02) and day-7 (p = 0.031).ConclusionsDuring the first three days of the postoperative period we cannot recommend routine CRP serum blood test monitoring in NOF# patients, as it is not diagnostic in the acute inflammatory phase for medical or surgical complications. |
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| Keywords: | Hip fracture Neck of femur CRP |
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