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Global polio eradication: Where are we in Europe and what next?
Institution:1. ECDC, 17183 Stockholm, Sweden;2. WHO EU, UN City, Marmorvej 51, DK-2100, Denmark;1. Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia;2. Pediatric Highly Intensive Care Unit, University of Milan, Milan, Italy;3. Immunization Action Coalition, St Paul, MN, USA;1. The Pediatric Infectious Disease Unit, Soroka University Medical Center, Beer-Sheva, Israel;2. Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel;3. Pediatric Infectious Disease Unit, Dana Children''s Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel;4. Pediatric Department and Infectious Diseases Unit, Shaare Zedek Medical Center Affiliated with Hebrew University-Hadassah School of Medicine, Jerusalem, Israel;1. Department of Pediatrics, Obstetrics & Gynecology and Preventive Medicine, Universitat Autònoma de Barcelona, Bellaterra, Spain;2. Pediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, Perugia, Italy;1. Vaccine-preventable Diseases and Immunization, World Health Organization Regional Office for Europe, Denmark;2. Global Immunization Division, Centres for Disease Control and Prevention, United States;1. University of Hradec Kralove, Faculty of Science, Hradec Kralove, Czech Republic;2. Charles University, Faculty of Medicine in Hradec Kralove, Department of Social Medicine, Hradec Kralove, Czech Republic;3. SUNY Upstate Medical University, Department of Pediatrics, Division of Pediatric Infectious Diseases, Syracuse, NY, USA;4. University of Defence, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic;5. Children’s Faculty Hospital Kosice, Department of Pediatric Infectious Diseases, Kosice, Slovakia;6. Biovomed, Hradec Kralove, Czech Republic
Abstract:The world was never so close to reach the polio eradication: only 37 cases notified in 2016 in only three countries, but the game is not yet at the end. The risk of polio outbreaks in the EU is smaller than it has ever been in the past, but it is not so small that we can ignore it. The EU MS must remain alert and plan and prepare for managing polio events or outbreaks because of the possible dire consequences. The IPV only vaccination schedule universally applied in EU has achieved satisfactory coverage, but constantly leaving small accumulating pockets of susceptible individuals. Moreover the IPV only schedule is not an absolute barrier against poliovirus silent transmission as demonstrated in the recent Israel outbreak. The availability of annually revised S.O.P. from WHO GPEI on the identification and response of a polio event, without local poliovirus transmission or a polio outbreak with sustained transmission, helps and challenge EU countries to update their polio national preparedness plans. The EU/EEA area, in fact, is a peculiar area regarding the polio risk both for its vaccination policy, the large polio vaccines manufactures and the constant immigration from areas at polio high risk, but also EU include cultural and financial potentials crucial to sustain the polio end game strategy and reach the benefit of a world without polio risk. Poliovirus eradication will continue to be challenged as long as there is the worldwide presence of polioviruses in laboratories and vaccine production plants. Most of the world’s OPV vaccines are produced in the EU and many laboratories and research centers store and handle polio viruses. EU Member States are engaged actively in implementing the poliovirus biocontainment plans that are part of the polio eradication strategy and to certify the destruction of poliovirus strains and potentially contaminated biological materials.
Keywords:Poliomyelitis  Vaccines and immunization  Public health policy  Infection control  Disease eradication
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