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Strategies for increasing uptake of vaccination in pregnancy in high-income countries: A systematic review
Affiliation:1. The Vaccine Confidence Project, London School of Hygiene & Tropical Medicine, Keppel St, London WC1E 7HT, United Kingdom;2. Imperial College Healthcare NHS Trust, South Wharf Road, St Mary''s Hospital, London W2 1NY, United Kingdom;1. Emory University, Department of Epidemiology and Laney Graduate School, Atlanta, GA, United States;2. Emory University, Rollins School of Public Health, Department of Behavioral Sciences and Health Education, and Division of Infectious Diseases, Department of Medicine, Atlanta, GA, United States;3. Emory University, Rollins School of Public Health, Hubert Department of Global Health, Atlanta, GA, United States;4. Emory University, Rollins School of Public Health, Department of Epidemiology, Atlanta, GA, United States;5. Emory University, School of Medicine, Department of Gynecology and Obstetrics, Atlanta, GA, United States;6. University of Kansas Medical Center, Department of Obstetrics and Gynecology, Kansas City, KS, United States;7. Emory University, Emory Vaccine Center and School of Medicine, Atlanta, GA, United States;8. Emory University, Department of Pediatrics, Atlanta, GA, United States;1. Public Health England, York, UK;2. Public Health England, Birmingham, UK;3. Public Health, Staffordshire University, Staffordshire, UK;1. Murdoch Children’s Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia;2. Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 50 Flemington Road, Parkville, VIC 3052, Australia;3. Faculty of Arts, Business, Law and Education, School of Social Sciences, University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia;4. Wesfarmers Centre of Vaccines & Infectious Diseases, Telethon Kids Institute, Perth Children''s Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia;5. Yale Institute for Global Health, Yale University, PO Box 208034, New Haven, CT 06520, United States;6. University of Sydney Susan Wakil School of Nursing and Midwifery, 88 Mallett St, Camperdown, NSW 2050, Australia;7. School of Public Health, Texas A&M University, College Station, TX 77845, United States;8. Robinson Research Institute and Adelaide Medical School, University of Adelaide, 55 King William St, North Adelaide, SA 5006, Australia;9. Women’s and Children’s Health Network, 72 King William Rd, North Adelaide, SA 5006, Australia;10. Perth Children’s Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia;11. School of Public Health, Curtin University, Kent Street, Bentley, WA 6102, Australia;12. Menzies School of Health Research and Charles Darwin University, PO Box 41096, Casuarina, NT 0811, Australia;13. Royal Children’s Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia;14. University of Sydney School of Public Health, A27 Fisher Rd, Camperdown, NSW 2006, Australia;15. Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia;1. Department of Paediatrics, Imperial College, London, UK;2. Department of Obstetrics and Gynaecology, Imperial College Healthcare NHS Trust, UK;3. Vaccines & Immunity Theme, MRC Unit, Gambia
Abstract:IntroductionVaccination in pregnancy is an effective method to protect against disease for the pregnant woman, foetus and new born infant. In England, it is recommended that pregnant women are vaccinated against pertussis and influenza. Improvement in the uptake of both pertussis and influenza vaccination among pregnant women is needed to prevent morbidity and mortality for both the pregnant women and unborn child.AimTo identify effective strategies in increasing the uptake of vaccination in pregnancy in high-income countries and to make recommendations for England.MethodsA systematic review of peer reviewed literature was conducted using a keyword search strategy applied across six databases (Medline, Embase, PsychInfo, PubMed, CINAHL and Web of Science). Articles were screened against an inclusion and exclusion criteria and papers included within the review were quality assessed.Results and conclusionsTwenty-two articles were included in the review. The majority of the papers included were conducted in the USA and looked at strategies to increase influenza vaccination in pregnancy. There is limited high quality evidence for strategies in high-income countries to increase coverage of pertussis and influenza vaccination in pregnancy. A number of strategies have been found to be effective; reminders about vaccination on antenatal healthcare records, midwives providing vaccination, and education and information provision for healthcare staff and patients. Future interventions to increase vaccination in pregnancy should be evaluated to ensure efficacy and to contribute to the evidence base.
Keywords:Pertussis vaccine  Influenza vaccine  Pregnancy  Vaccine hesitancy  Maternal vaccination  Strategies  EPHPP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Effective Public Health Practice Project  GP"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  General Practitioner  NHS"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  National Health Service  PHE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Public Health England  PRISMA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Preferred Reporting Items for Systematic Reviews and Meta-Analyses  RCT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0090"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Randomised Control Trials  WHO"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  k0100"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  World Health Organization
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