Interstitial lung disease: Elementary lesions and diagnosis |
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| Affiliation: | 1. Department of Pathology, Abderrahman Mami Hospital, Tunisia;2. Université Tunis El Manar, Faculté de Médecine de Tunis, Tunisia;1. Department of Internal Medicine, Marques de Valdecilla University Hospital, Santander, Cantabria, Spain;2. Department of Ophthalmology, Marques de Valdecilla University Hospital, Santander, Cantabria, Spain;1. Division of Surgical Pathology & Cytopathology, University of Virginia Medical Center, 1215 Lee Street, Charlottesville, VA 22908-0214, USA;2. PRW Laboratories, Charlottesville, VA, USA |
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| Abstract: | An effective approach to the diagnosis of interstitial lung diseases requires a standardized method of evaluation with a structured analysis, beginning with scanning microscopy and proceeding to a more detailed assessment. This article is structured around the histologic patterns defined by Leslie that facilitate this process. They include acute injury, fibrosis, cellular infiltrates, airspace filling, formation of nodules, and minimal changes. Illustrations of all of these patterns are provided, together with a discussion of the disease entities that manifest them. |
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