Rapid Detection of ESBL-Producing Enterobacteriaceae in Blood Cultures |
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| Authors: | Laurent Dortet Laurent Poirel Patrice Nordmann |
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| Affiliation: | Institut National de la Santé et de la Recherche Médicale, Le Kremlin–Bicêtre, France (L. Dortet, L. Poirel, P. Nordmann); ;University of Fribourg, Fribourg, Switzerland, Department of Medicine (L. Poirel, P. Nordmann); ;Hôpital Fribourgeois-hôpital Cantonal, Fribourg (P. Nordmann) |
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| Abstract: | We rapidly identified extended-spectrum β-lactamase (ESBL) producers prospectively among 245 gram-negative bacilli–positive cultured blood specimens using the Rapid ESBL Nordmann/Dortet/Poirel test and direct bacterial identification using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. This combination identified ESBL-producing Enterobacteriaceae within 30 min and had high predictive values. |
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| Keywords: | Resistance, bacteria, antibiotic, antibacterial, gram-negative, β -lactam, cephalosporins, cephamycins, carbapenems, ESBL, Nordmann/Dortet/Poirel test, Enterobacteriaceae, MALDI-TOF, mass spectrometry, rapid diagnostic test |
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