| 31P 磁共振波谱对心肌梗死能量代谢变化的评价 |
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| 引用本文： | 赵海涛,陆军,张卓立,孙立军,魏光全,韩月东,常英娟,张劲松,宦怡. 31P 磁共振波谱对心肌梗死能量代谢变化的评价[J]. 中国医学影像技术, 2003, 19(9): 1128-1130 |
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| 作者姓名： | 赵海涛 陆军 张卓立 孙立军 魏光全 韩月东 常英娟 张劲松 宦怡 |
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| 作者单位： | 1. 第四军医大学西京医院放射科,陕西,西安,710032
2. 第四军医大学西京医院放疗科,陕西,西安,710032 |
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| 摘 要： | 目的利用 31P 磁共振波谱评价心肌梗死后心肌能量代谢的变化,区分存活心肌与梗死心肌.方法对10例证实为前壁心梗的患者,CABG(coronary artery bypass grafting)治疗术前(2～8天)及术后(4～6个月)行电影MRI和 31P MRS检查,检测前壁心肌PCr、ATP、Pi,并计算PCr/γ-ATP、PCr-SNR及γ-ATP-SNR,确定前壁心肌节段心功能恢复情况,观察梗死前壁节段心肌 31P MRS检测高能磷酸盐变化与心肌活力的关系.对照组10例志愿者参加研究.结果前壁心肌梗死后存活心肌(7例) 31P MRS显示PCr-SNR和γ-ATP-SNR与健康志愿者比较无显著差异(P>0.05).MRI检测无活力心肌3例, 31P MRS基本未测出PCr峰且γ-ATP-SNR与健康志愿者比较显著减低(P<0.05).结论 31P 磁共振波谱可用于评价心肌梗死后心肌能量代谢的变化,是非侵入性心肌高能磷酸盐监测的有利工具.
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| 关 键 词： | 磁共振波谱 存活心肌 能量代谢 |
| 文章编号： | 1003-3289(2003)09-1128-03 |
| 收稿时间： | 2003-05-13 |
| 修稿时间： | 2003-05-13 |
Evaluation of the Changes in Myocardial Infarction |
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| ZHAO Hai-tao,LU Jun,ZHANG Zhuo-li,SUN Li-jun,WEI Guang-quan,HAN Yue-dong,CHANG Ying-juan,ZHANG Jin-song and HUAN Yi. Evaluation of the Changes in Myocardial Infarction[J]. Chinese Journal of Medical Imaging Technology, 2003, 19(9): 1128-1130 |
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| Authors: | ZHAO Hai-tao LU Jun ZHANG Zhuo-li SUN Li-jun WEI Guang-quan HAN Yue-dong CHANG Ying-juan ZHANG Jin-song HUAN Yi |
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| Affiliation: | Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China;Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China |
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| Abstract: | |
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| Keywords: | Magnetic resonance spectroscopy Viable myocardium Energy metabolism |
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