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正交实验法优选匙羹藤总皂苷的提取工艺
引用本文:侯会绒,吴向阳,仰榴青,姜松,傅海珍,范群艳,朱晓宦.正交实验法优选匙羹藤总皂苷的提取工艺[J].时珍国医国药,2006,17(6):917-918.
作者姓名:侯会绒  吴向阳  仰榴青  姜松  傅海珍  范群艳  朱晓宦
作者单位:1. 江苏大学生物与环境工程学院,江苏,镇江,212013
2. 江苏大学化学化工学院,江苏,镇江,212013
3. 江苏大学药学院,江苏,镇江,212013
基金项目:江苏大学微纳米科学技术研究开放基金资助项目
摘    要:目的研究匙羹藤总皂苷的最佳提取工艺条件。方法以匙羹藤总皂苷得率为指标,采用正交实验法考察乙醇浓度、料液比、提取时间、提取次数等4个因素对提取效果的影响。结果匙羹藤总皂苷的最佳提取工艺:乙醇浓度70%,料液比1∶6,提取时间3 h,提取2次。结论此最佳工艺可用于匙羹藤总皂苷的提取。

关 键 词:正交实验法  匙羹藤  总皂苷  提取工艺
文章编号:1008-0805(2006)06-0917-02
收稿时间:2006-03-21
修稿时间:2006-05-18

Study on the Process of the Total Saponins of Gymnema sylvestre by Orthogonal Design
HOU Hui-rong,WU Xiang-yang,YANG Liu-qing,JIANG Song,FU Hai-zhen,FAN Qun-yan,ZHU Xiao-huan.Study on the Process of the Total Saponins of Gymnema sylvestre by Orthogonal Design[J].Lishizhen Medicine and Materia Medica Research,2006,17(6):917-918.
Authors:HOU Hui-rong  WU Xiang-yang  YANG Liu-qing  JIANG Song  FU Hai-zhen  FAN Qun-yan  ZHU Xiao-huan
Institution:1. Shool of Biology and Environment Engineering , Jiangsu University , Zhenjiang 212013, China; 2. Chemistry and Chemical Engineering, Jiangsu University , Zhenfiang 212013, China ; 3. School of Pharmacy, Jiangsu University, Zhenjiang, 212013, China
Abstract:ObjectiveTo study the optimum extraction process of the total saponins of Gymnema sylvestre.MethodsThe orthogonal test were used,in which the output of the total saponins was regarded as an examine target and the influence of four factor in the extraction of effective substance were studied.The four factors are the concentration of ethanol,ratio of material to liquid,the time of extraction and the mumber of extraction.ResultsThe optimum extraction process of the total saponins of Gymnema sylvestre has been established as follows:the concentration of ethanol 70%,ratio of material to liquid 1:6,extraction time 3h,2 times.ConclusionThe optimum process is applicable for extraction of the total saponins of Gymnema sylvestre.
Keywords:Orthogonal test  Gymnema sylvestre  Total saponins  Extraction process
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