The Origin and Evolution of Human T-Cell Lymphotropic Virus Types I and II |
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| Authors: | Suzuki Yoshiyuki Gojobori Takashi |
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| Affiliation: | (1) Center for Information Biology, National Institute of Genetics, Mishima, 411, Japan;(2) Department of Microbiology, Akita University School of Medicine, Akita, 010, Japan |
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| Abstract: | Studies on human T-cell lymphotropic virus types I (HTLV-I) and II (HTLV-II) are briefly reviewed from the viewpoint of molecular evolution, with special reference to the evolutionary rate and evolutionary relationships among these viruses. In particular, it appears that, in contrast to the low level of variability of HTLV-I among different isolates, individual isolates form quasispecies structures. Elucidating the mechanisms connecting these two phenomena will be one of the future problems in the study of the molecular evolution of HTLV-I and HTLV-II. |
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| Keywords: | human T-cell lymphotropic virus molecular evolution evolutionary rate phylogenetic tree genetic variation geographical distribution |
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