富含血管基质层细胞自体脂肪颗粒移植纠正颜面萎缩的临床观察

目的:探讨富含血管基质层细胞(stromal vascular fraction,SVF)的自体脂肪颗粒注射移植在面部萎缩中的应用,达到提高脂肪存活率效果。方法:从2011年8月到2013年2月,我们选择6例半侧颜面萎缩的患者,于下腹部采用肿胀吸脂术获得自体颗粒脂肪,通过静置,纯化后采用多层次、多隧道、多点的注射方法,充填修复颜面部凹陷畸形。术后3个月随访,效果欠佳者即进行第二次手术脂肪颗粒移植,直至效果满意为止。结果:本组6例半侧颜面萎缩患者,随访3～12个月(平均6.5个月),充填后脂肪吸收率低,面部两侧基本达到对称,效果满意。结论:应用自体颗粒脂肪移植修复半侧颜面萎缩操作简单,创伤性小,效果理想,对于轻度中度的颜面萎缩患者而言,是一种较为理想的简单有效的治疗方法,值得推广。

Treatment of facial dysplasia atrophy by autologous fat granule injection which was rich in stromal vascular fraction

Objective To evaluate an improved treatment of an autologous fat granule injection which was rich in stromal vascular fraction （SVF） for facial dysplasia atrophy. Methods 6 patients with facial dysplasia atrophy underwent an improved treatment by the rich in SVF autologous fat granule injection for their diseases. The autologous fat granules were harvested from patient＇s abdomen by liposuction with 20ml syringe under the tumescent anesthesia.After remove redundance water by placed in an upright position for 3 minutes the fat granules were injected to the facial introcession area with Multi- plane multi-tunnel and multi-point method. Results All the patients had a satisfactory symmetrical face after the injection, the follow-up results were good after one year. Conclusion The fat granule injection is a simple treatment for the facial dysplasia atrophy with satisfactory effect and no injury, for the slight or medium patients this method is an ideal treatment.