Value and utility of disease-specific and generic instruments for assessing disability in patients with migraine,and their relationships with health-related quality of life |
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Authors: | Email author" target="_blank">Alberto?RaggiEmail author Matilde?Leonardi Gennaro?Bussone Domenico?D’Amico |
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Institution: | (1) Neurology, Public Health and Disability Unit, Scientific Directorate, Neurological Institute C. Besta, IRCCS Foundation, Via Celoria 11, 20133 Milan, Italy;(2) Headache Centre, Neurological Institute C. Besta, IRCCS Foundation, Via Celoria 11, 20133 Milan, Italy |
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Abstract: | The aim of this paper is to explore the relationships between health-related quality of life (HRQoL), assessed with the Short
Form-36 (SF-36), and disability in adult migraineurs using both disease-specific and generic tools, the WHO Disability Assessment
Schedule II (WHO-DAS II) and with the Migraine Disability Assessment questionnaire (MIDAS). Significant differences were observed
between patients with minimal/mild and moderate/severe MIDAS disability grades for Role Physical, Bodily Pain, General Health,
Vitality, Social Functioning and Physical Composite Score of the SF-36; in the WHO-DAS II for household activities, participation
in society and for summary score. WHO-DAS II and MIDAS provide complementary information on the intensity and the frequency
of problems in performing daily activities, and could be used jointly. Our findings indicate that these issues are relevant
for patients’ health status and should be taken into account in future research on migraine as important secondary outcomes
of treatment interventions. |
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