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Inappropriate Angiogenic Response as a Novel Mechanism of Duodenal Ulceration and Impaired Healing
Authors:Xiaoming Deng  Ximing Xiong  Tetyana Khomenko  Zsuzsanna Sandor  Klara Osapay  Ganna Tolstanova  Joseph Shiloach  Longchuan Chen  Judah Folkman  Sandor Szabo
Institution:(1) Diagnostic & Molecular Medicine, VA Medical Center, 5901 E. 7th Street, Long Beach, CA 90822, USA;(2) Department of Pathology, University of California-Irvine, Irvine, CA 92697, USA;(3) Medical Health Care Groups, VA Medical Center, 5901 E. 7th Street, Long Beach, CA 90822, USA;(4) Department of Medicine, University of California-Irvine, Irvine, CA 92697, USA;(5) Biotechnology Unit, NIDDK, NIH Bldg 14A, Room 173, Bethesda, MD 20892, USA;(6) Departments of Pediatric Surgery and Cell Biology, Children’s Hospital, Harvard Medical School, Boston, MA 02115, USA;(7) Departments of Pathology and Pharmacology, University of California-Irvine, Irvine, CA 92697, USA
Abstract:

Background  

Despite recent advances and better understanding of the etiology and the pathogenesis of gastrointestinal ulcer diseases, e.g., duodenal ulcer, the molecular events leading to ulcer development, delayed healing, and recurrence remain poorly elucidated.
Keywords:
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