The postthrombotic syndrome |
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Authors: | Raffaele Pesavento Sabina Villalta Paolo Prandoni |
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Institution: | (1) Thromboembolic Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Via Giustiniani, 2, 35128 Padua, Italy;(2) Department of Internal Medicine, Civil Hospital of Treviso, Treviso, Italy |
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Abstract: | Following deep vein thrombosis (DVT), one of every two patients will develop postthrombotic syndrome (PTS), which causes remarkable
consequences on the socioeconomic level. Residual thrombosis is an important predictor of PTS, and severe early symptoms,
old age, obesity, improper anticoagulation, recurrent thrombosis and varicose veins are major risk factors. Diagnosis of PTS
is mainly based on the clinical findings for patients with a history of DVT, while in those without it, instrumental diagnosis
might help in detecting a previous DVT. Prompt administration of adequate compression elastic stockings (ECS) in patients
with symptomatic DVT reduces the frequency of PTS by half. Usually, the management of an established PTS is demanding, and
often discouraging. However, when carefully supervised and instructed to wear proper ECS, more than 50% of patients either
remain quiescent or improve during long-term follow-up. |
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Keywords: | |
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