| A study of portal vein embolization with absolute ethanol injection in cirhotic rats |
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| 作者姓名： | LU Ming De YIN Yiao Yu and REN Wei |
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| 作者单位： | LU Ming De，YIN Yiao Yu and REN Wei |
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| 摘 要： | ＩＮＴＲＯＤＵＣＴＩＯＮＰｏｒｔａｌｖｅｉｎｅｍｂｏｌｉｚａｔｉｏｎ（ＰＶＥ）ｐｌａｙｓａｎｉｍｐｏｒｔａｎｔｒｏｌｅｉｎｔｈｅｍａｎａｇｅｍｅｎｔｏｆｈｅｐａｔｏｃｅｌｕｌａｒｃａｒｃｉｎｏｍａ（ＨＣＣ）．Ｗｅｍｏｄｉｆｉｅｄｔｈｅｃｏｎｖｅｎｔｉ...
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A study of portal vein embolization with absolute ethanol injection in cirrhotic rats |
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| LU Ming De,YIN Yiao Yu and REN Wei.A study of portal vein embolization with absolute ethanol injection in cirhotic rats[J].World Journal of Gastroenterology,1998,4(5). |
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| Authors: | LU Ming-De YIN Yiao-Yu REN Wei |
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| Abstract: | AIM To investigate the effects of portal vein embolization (PVE) with absolute ethanol injection on the cirrhotic livers. METHODS Absolute ethanol was injected intraportally into normal and cirrhotic SD rats and the changes of the animals in anatomy, pathology, liver function as well as portal hemodynamics were observed. RESULTS At a dose of 0 05mL/100g of ethanol, the survival rate was 100% in normal rats compared with 40 9% in cirrhotic rats. PVE in the cirrhotic rats with 0 03mL/100g of ethanol, caused significant hypertrophy in non embolized lobes, mild or moderate damage to the hepatic parenchyma, slight and transient alterations in liver function, portal pressure and portal flow. CONCLUSION PVE with absolute ethanol injection in the setting of liver cirrhosis could be safe at an appropriate dose, and precautions aimed at preserving liver function were preferable. |
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| Keywords: | liver cirrhosis/therapy embolization therapeutic absolute ethanol portal vein hemodynamics |
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