肃肺和胃法治疗外感咳嗽的疗效机理和临床研究

目的观察内伤基础上外感咳嗽的治疗方法.方法.选择了90例胃内伤基础上外感咳嗽的患者随机分为3组,治疗组治以肃肺和胃法,用自拟汤药治疗;对照组Ⅰ肺胃同治,急支糖浆合加味保和丸;对照组Ⅱ单纯治肺,仅用急支糖浆,疗程均为7 d.结果.肺胃同治、肃肺和胃法在改善临床症状、缩短疗程等方面明显优于对照组,具有显著性差异,表明这种立法与处方是可行的,具有较高的临床价值.结论.对外感咳嗽仔细辨别其有无内伤基础,辨证准确、切中病机、药证相合是临床疗效的根本所在.

Clinical Trial of the Therapy of Clearing Lung and Harmonizing Stomach for the Treatment of the Cough Caused by Exogenous Pathogens:Investigation of the Mechanism of the Effects

Objective To investigate the mechanism of effects of the TCM therapy of clearing lung and harmonizing stomach in the treatment of gastric internal impairment complicated by the cough caused by exogenous pathogens.Methods 90 Cases of gastric internal impairment complicated by the cough caused by exogenous pathogens were randomly divided into 3 groups: the treating group treated by the therapy of clearing lung and harmonizing stomach (with a self-designed decoction ), the control group-1 treated by the therapy of treating both the lung and stomach (with Jizhi Syrup and the Modified Baohe Pills), and the control group-2 treated by therapy of treating the lung only (with Jizhi Syrup only); the treatment course was equally 7 days for all the three groups. Results The TCM therapy of clearing lung and harmonizing stomach showed much better effects than other therapies used in the clinical trial, as far as the relief of the clinical symptoms and the shortening of the treatment course were concerned ( P <0.01), which suggested that the therapy and the relevant formula were feasible and possessed a relatively high clinical value. Conclusion In the treatment of the cough caused by exogenous pathogens, the key points are careful differentiation of gastric internal impairment, clearly understanding of the pathogenesis, and a perfect unison of the prescribed drugs and the diagnosed syndromes.