937例药物不良反应报告分析

目的分析药品不良反应(ADR)发生的规律和特点,减少ADR的发生,提高临床用药的合理性。方法对937例药品不良反应报告进行统计,分别从患者年龄、性别、药品种类、临床表现、给药途径等方面进行统计分析。结果 937例报告中发生ADR患者男性多于女性,ADR涉及的药品多为抗微生物药物,ADR的临床表现主要以皮肤及其附件损害为主。所有的用药途径中静脉滴注用药发生ADR的几率最高。结论收集整理不良反应药物报告,定量分析,综合评价其信息有利于促进临床合理用药,保证患者用药安全。

Analysis of 937 adverse drug reaction cases

Objective To investigate the characteristics of hospital adverse drug reaction (ADR) and to reduce its incidence rate and provide some rational clinical guidance .Method 937 reports of adverse reactions caused by drugs were collected and statistically analyzed in respect of patients′ age and sex ,involved drugs ,clinical manifestations ,and routes of administration .Result In 937 ADR cases ,male was more than female .The most drugs related to ADR were anti-infective which occupied large quantity in the constituent ratio of ADR .The most common clinical manifestations of damage were skin and its appendages ,and most ADR were induced by intravenous drop infusion .Conclusion The collection and analysis of ADR were helpful to ensure and promote safe and rational clinical medication .