CYP2E1 Pst Ⅰ/Rsa Ⅰ polymorphism and colorectal cancer risk:A meta-analysis |
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作者单位: | Guo-Wu Zhou,Qiang Li(Department of Respiration, Changhai Hospital, Second Military Medical University, Shanghai 200433, China);Jia Hu(Department of Oncology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China) |
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摘 要: | AIM:To clarify the association between CYP2E1 PstⅠ/RsaⅠ polymorphism and susceptibility to colorectal cancer.METHODS:A meta-analysis based on 10 eligible casecontrol studies involving 4979 cases and 6012 controls was carried out to summarize the data on the association between CYP2E1 RsaⅠ/PstⅠ polymorphism and colorectal cancer risk.RESULTS:In comparison of the homozygote c2c2 and c2 carriers(c1c2 + c2c2) and the homozygous wild-type genotype(c1c1),no association was found between CYP2E1 RsaⅠ/PstⅠ polymorph...
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关 键 词: | Cytochrome P450 2E1 PstⅠ/RsaⅠ polymorphism Colorectal cancer Cancer susceptibility Metaanalysis |
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