| 艾灸对运动性疲劳大鼠肝糖原及肝脏超微结构的影响 |
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| 作者姓名： | Lu J Ge GL Zhang HL Yin ZZ Li ZG Zhang X Wu ZW Guo MW Zhang LF Zhao BX |
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| 作者单位： | 1. 北京中医药大学针灸推拿学院,北京,100029
2. 北京中医药大学中医药科技中心,北京,100029 |
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| 基金项目： | 北京中医药大学校级科研课题,国家"973"课题 |
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| 摘 要： | 目的:从艾灸对肝糖原和肝细胞超微结构的影响,探讨艾灸消除运动性疲劳的作用机制。方法:将SD雄性大鼠随机分为安静对照组、模型组和艾灸组,每组11只。采用21 d力竭游泳方式制作运动性疲劳模型。从第1天造模起即用艾炷灸双侧"足三里"穴,每穴各3壮,隔日1次,共灸11次。采用蒽酮法检测肝糖原,并观察电镜下肝细胞超微结构。结果:与安静对照组比较,模型组肝糖原含量显著降低(P<0.01);艾灸组与模型组比较,肝糖原含量显著增高(P<0.05)。电镜观察显示模型组肝糖原稀疏、减少,肝细胞线粒体和粗面内质网结构不清晰;而艾灸组肝糖原较丰富,线粒体和粗面内质网结构基本清晰。结论:艾灸消除运动性疲劳的部分作用机制,可能是通过调节肝糖原含量、促进血糖的稳定,并改善肝细胞的超微结构、缓解肝细胞损伤而实现。
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| 关 键 词： | 疲劳 力竭运动 艾灸 肝糖原 肝细胞超微结构 |
Effect of moxibustion on hepatic glycogen and ultrastructure of exercise-induced fatigue rats |
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| Lu J,Ge GL,Zhang HL,Yin ZZ,Li ZG,Zhang X,Wu ZW,Guo MW,Zhang LF,Zhao BX.Effect of moxibustion on hepatic glycogen and ultrastructure of exercise-induced fatigue rats[J].Acupuncture Research,2011,36(1):32-35. |
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| Authors: | Lu Jun Ge Gui-ling Zhang Hong-lin Yin Zhen-zhen Li Zhi-gang Zhang Xin Wu Zhou-wen Guo Meng-wei Zhang Lu-fen Zhao Bai-xiao |
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| Institution: | LU Jun,GE Gui-ling1,ZHANG Hong-lin,YIN Zhen-zhen,LI Zhi-gang,ZHANG Xin1,WU Zhuo-wen,GUO Meng-wei,ZHANG Lu-fen,ZHAO Bai-xiao(School of Acu-moxibustion and Tuina,Beijing University of Chinese Me-dicine,Beijing 100029,China,1Center for Science and Technology of Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029) |
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| Abstract: | Objective To observe the effect of moxibustion of Zusanli(ST 36) on hepatic glycogen level and ultrastructure changes in exercise-induced fatigue rats.Methods Thirty-three SD rats were randomly and equally divided into control,model and moxibustion groups.The fatigue model was established by forcing the rat to have a loaded exhaustion swim,once daily for 21 days.Moxibustion was applied to bilateral Zusanli for about 30 min,once every other day for 11 times.The hepatic glycogen content was detected by chroma... |
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| Keywords: | Fatigue Exhaustive exercise Moxibustion Hepatic glycogen Ultrastructure of hypatocytes |
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