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| 广枣对肾缺血再灌注损伤的保护作用研究 | |
| 引用本文： | 张振涛,吴仁奇,张威,张娟. 广枣对肾缺血再灌注损伤的保护作用研究[J]. 现代中西医结合杂志, 2003, 12(18): 1942-1943 |
| 作者姓名： | 张振涛 吴仁奇 张威 张娟 |
| 作者单位： | 1. 内蒙古医学院,内蒙古,呼和浩特,010059 2. 河北省保定市第一中医院,河北,保定,071000 3. 中国人民解放军第252医院,河北,保定,071000 |
| 摘 要： | 目的 探讨广枣对急性肾缺血再灌注损伤的肾脏的保护作用。方法 通过建立大鼠急性肾缺血再灌注损伤模型 ,观察广枣对肾缺血再灌注后血中丙二醛 (MDA)、超氧化物歧化酶 (SOD)以及肾组织Na+ ,K+ -ATP酶和Ca2 + -ATP酶活性的影响。结果 使用广枣后 ,MDA明显下降 ,SOD ,Na+ ,K+ -ATP酶和Ca2 + -ATP酶活性显著上升。结论 广枣对急性肾缺血再灌注损伤的肾脏有显著的保护作用 |
| 关 键 词： | 广枣 肾缺血再灌注 保护作用 |
| 文章编号： | 1008-8849(2003)18-1942-02 |
| 修稿时间： | 2003-02-18 |
Study of protective function of Scabiosae from renal ischemia-reperfusion injury |
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| ZHANG Zhen-tao ,WU Ren-qi ,ZHANG Wei ,ZHANG Juan. Study of protective function of Scabiosae from renal ischemia-reperfusion injury[J]. Modern Journal of Integrated Chinese Traditional and Western Medicine, 2003, 12(18): 1942-1943 | |
| Authors: | ZHANG Zhen-tao WU Ren-qi ZHANG Wei ZHANG Juan |
| Affiliation: | ZHANG Zhen-tao 1,WU Ren-qi 1,ZHANG Wei 2,ZHANG Juan 3 |
| Abstract: | Objective It is to investigate the protective func tion of Scabiosae on kidney against acute ischemia-reperfusion injury. Methods The renal ischemia-re perfusion models were established. The effect of Scabiosae on MDA, SOD in blood and Na +, K +-ATP ase , Ca 2+ -ATP ase in renal tissue were measu red. Results The conte nt of MDA decreased obviously and the contents of SOD, Na +, K +-ATP ase , Ca 2+ -ATP ase increased significantly. Conclusion Sca biosae can protect kidney from ischemia-reperfusion injury. |
| Keywords: | Scabiosae renal ischemia-reperfusion protect fun ction |
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