中晚期肝癌死亡原因探讨

本文报告中晚期肝癌295例,院内死亡51例,死亡率为17.3％。手术组(251)与非手术组(44)的死亡率分别为17.5％和15.9％,死亡时间分别为术后16.2天和入院后20.8天。主要死于休克,肝肾综合征、肝功能衰竭、癌破裂及上消化道大出血等,死因分别为6.8％、6.8％、6.1％6.1％和4.4％。作者建议作好术前肝功能储备的估计,以减少因出血、肝衰及感染等原因造成的死亡。

Causes of Death in Patients with Advanced Hepatocellular Carcinoma

Of 295 cases of hepatocellular carcinoma treated at the authors' hospital, 51 died in hospital with a mortality rate of 17.3% (surgesy 17.5%, non-surgery 15.9%). The mean time to death was 16.2 days after surgery or 20.8 days after admission. The main causes of death included shock (6.8%), hepato-renal syndrome (6.8%), hepatic failure (6.1%), rupture of tumor mass (6.1%) and massive hemorrhage in upper GI tract (4.4%). It is suggested that the liver function should be thoroughly estimated before surgery in order to reduce the occurrence of hemorrhage, hepatic failure or infection.