| 贝尼地平和培哚普利对老年高血压病伴蛋白尿患者肾功能的影响 |
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| 引用本文： | 董波,屈晓冰.贝尼地平和培哚普利对老年高血压病伴蛋白尿患者肾功能的影响[J].中国现代医药杂志,2011,13(11):54-56. |
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| 作者姓名： | 董波 屈晓冰 |
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| 作者单位： | 1. 湖南省马王堆医院,湖南长沙,410016
2. 中南大学湘雅二医院 |
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| 摘 要： | 目的比较新型钙通道阻滞剂贝尼地平与血管紧张素转换酶抑制剂培哚普利对老年高血压病伴蛋白尿患者肾脏保护作用的差别。方法将60例24h尿蛋白总量<1g的老年高血压病患者,随机分为贝尼地平组(A组)与培哚普利组(B组),分别给予贝尼地平与培哚普利治疗12月,比较A、B两组治疗前后收缩压(SBP),舒张压(DBP),24h尿蛋白(Pro)、血清肌酐(Scr)、肾小球滤过率(GFR)的差别。结果①治疗前A、B两组SBP、DBP、Pro、Scr、GFR无显著性差异(P>0.05);②A、B两组治疗后SBP、DBP、Scr较治疗前有显著下降,GFR均明显升高(P<0.05);③治疗后AB两组间SBP、DBP、Scr、GFR无明显差异(P>0.05)。结论贝尼地平与培哚普利比较,对老年高血压伴蛋白尿的患者,具有相似的肾脏保护作用。
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| 关 键 词： | 贝尼地平 培哚普利 老年高血压 蛋白尿 肾小球滤过率 |
Renal function effects of benidipine and perindopril in elderly hypertensive patients with proteinuria |
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| Dong Bo,Qu Xiaobing.Renal function effects of benidipine and perindopril in elderly hypertensive patients with proteinuria[J].Modern Medicine Journal of China,2011,13(11):54-56. |
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| Authors: | Dong Bo Qu Xiaobing |
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| Institution: | Dong Bo,Qu Xiaobing.Ma Wangdui Hospital of Hunan Province,Changsha 410016 |
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| Abstract: | Objective To compare the difference of the new type of calcium channel blockers benidipine and angiotensin-converting enzyme inhibitor perindopril in elderly hypertensive patients with proteinuria in patients with renal protective effect.Methods The 24h urine total protein <1g of 60 elderly patients with hypertension were randomly assigned benidipine group (A guoup) and perindopril group (B group) were treated with benidipine or perindopril for 12 months,systolic blood pressure (SBP),diastolic blood pressur... |
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| Keywords: | Benidipine Perindopril Elderly hypertension Proteinuria Glomerular filtration rate |
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