Thromboxane B2 Production During Erection |
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| Authors: | M.S. BORNMAN R.C. FRANZ D.J. JACOBS and D.J. DU PLESSIS |
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| Affiliation: | Department of Urology and Department of Surgery, Pretoria University Medical School, Pretoria/South Africa |
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| Abstract: | The effect of erection on 6-keto-PGF1 alpha and thromboxane B2 in penile blood during electrically evoked erection was studied in the chacma baboon. 6-keto-PGF1 alpha remained at a low concentration, but thromboxane B2 showed a statistically significant rise 8-10 minutes after commencement of erection. Elevated thromboxane B2 during erection may potentiate platelet aggregation and may be one of the key events in the pathogenesis of ageing impotence. |
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| Keywords: | 6-keto-PGF1 α thromboxane B2 erection ageing impotence |
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