Language lateralization by Wada test and fMRI in 100 patients with epilepsy |
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| Authors: | Woermann F G Jokeit H Luerding R Freitag H Schulz R Guertler S Okujava M Wolf P Tuxhorn I Ebner A |
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| Affiliation: | Mara Hospital and Institute for Interdisciplinary Epilepsy Research, Bethel Epilepsy Centre, Bielefeld, Germany. fgw@mara.de |
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| Abstract: | Comparing the determination of language dominance using fMRI with results of the Wada test in 100 patients with different localization-related epilepsies, the authors found 91% concordance between both tests. The overall rate of false categorization by fMRI was 9%, ranging from 3% in left-sided temporal lobe epilepsy (TLE) to 25% in left-sided extratemporal epilepsy. Language fMRI might reduce the necessity of the Wada test for language lateralization, especially in TLE. |
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