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急性髓系白血病细胞核形态计量值与预后分析
引用本文:杨碧云 杨平南 等. 急性髓系白血病细胞核形态计量值与预后分析[J]. 江西医学院学报, 1999, 39(4): 39-41
作者姓名:杨碧云 杨平南 等
作者单位:Department of Hematology,Second Affiliated Hospital of Jiangxi Medical College,Nanchang,330006
摘    要:探讨急性髓系白血病(AML)患者细胞核的形态定量值的临床意义。方法:运用体视学方法在普通光镜下手工测试73例AML细胞核形态值,对一个月内死亡与生存的患者进行对比分析。结果:死亡组细胞核长轴(NL)、短轴(NS)、平均轴(NM)及核面积(Vα)值均明显小于生存组(P<0.05),且死亡组各参数低于本组平均值者明显增多(P<0.01)。结论:提示AML首次骨髓细胞核形态值的变化可能有预后意义

关 键 词:急性髓系白血病  形态计量学  预后

Morphometric Study of Nuclei of Leukemic Cells in Patients with Acute Myeloid Leukemic
Yang Biyun Yang Pingnan Cao Ruisheng Li Huihui. Morphometric Study of Nuclei of Leukemic Cells in Patients with Acute Myeloid Leukemic[J]. Acta Academiae Medicinae Jiangxi, 1999, 39(4): 39-41
Authors:Yang Biyun Yang Pingnan Cao Ruisheng Li Huihui
Abstract:Objective:To investigate the clinical significance of morphometric values of leukemic cellular nucleis in patients with Acute Myeloid Leukemia (AML).Methods:The leukemic cellular nuclei of 73 AML patients were measured with manual test system under light microscope.The morphometric values of dead and in survived AML patients within a month were analysed.Results:The measured values of long axis (NL),short axis (NS),mean axis (NM),profile area of nucleus (Na) were significantly lower in the dead patients group than those in the survived group ( P <0.05).The amount of AML patients were increased markedly whose cellular nucleus parameters were lower comparing with mean values of 73 AML patients.Conclusion:The morphometric value of BM cellular nucleuses in newly diagnosed AML patients might have a significance of predicting prognosis.
Keywords:leukemia  myeloid  acute  morphomectry  
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