愈疡胶囊对正常小鼠外周血和脾T淋巴细胞亚群的影响

目的：研究愈疡胶囊对正常小鼠外周血和脾T淋巴细胞亚群的影响.方法：24只雄性昆明小鼠,随机分为正常对照组、阳性对照组、愈疡胶囊高剂量组和愈疡胶囊低剂量组 分别灌胃蒸馏水及相应药物,流式细胞仪测定外周血和脾淋巴细胞T淋巴细胞亚群.结果：与正常对照组比较,给药组能明显升高小鼠外周血和脾淋巴细胞T淋巴细胞亚群CD4分子表达量（P〈0.01或P〈0.001）.结论：愈疡胶囊可增强正常小鼠的细胞免疫功能,为该药的免疫增强作用提供了实验依据.

Effects of Yuyang Capsule to T Lymphocyte Subsets in Peripheral Blood and Spleen of the Normal Mice

Objective： To Study the effects of yuyang capsule to T lymphocyte subsets in peripheral blood and spleen of the normal mice. Method： Twenty-four male Kunming mices were randomly divided into control group, positive control group, high dose group and low dose group of yuyang capsule, which were fed distilled water and the corresponding drugs. Then T-lymphocyte subsets in peripheral blood and spleen were detected with the flow cytometry. Result： Compared with the normal control group, treatment group were significandy increase the T-lymphocyte subsets CD4 molecule expression in peripheral blood and spleen, and the difference between the high dose group and control group was significant （P 〈 0. 01 or P 〈 0. 001 ） . Besides, the treatment groups could increase T-lymphocyte subsets CD4/CD8 ratio in peripheral blood and spleen. Conclusion： Yuyang capsule can enhance cellular immune function in normal mice, which provides an experimental basis of yuyang capsule to enhance the immune function.