| 锌对大鼠发育脑海马超微结构的影响 |
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| 引用本文： | 孔祥英,卞修武.锌对大鼠发育脑海马超微结构的影响[J].第三军医大学学报,1996,18(4):340-343. |
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| 作者姓名： | 孔祥英 卞修武 |
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| 作者单位： | 第三军医大学附属西南医院儿科 基础部病理解剖学教研室 |
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| 摘 要： | 通过电镜观察从哺乳期开始缺锌（ＺＤ）、高锌（ＺＥ）大鼠脑海马ＣＡ３区的超微结构，发现ＺＤ组锥体细胞突触小泡减少，ＺＥ组锥体细胞、胶质细胞、突触等均有不同程度变性，突触小泡破裂。结果提示海马超微结构的变化是ＺＤ和ＺＥ影响学习记忆的物质基础或机理之一。
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| 关 键 词： | 缺锌 高锌 海马 超微结构 |
Effects of zinc on the ultrastructure of hippocampus in developing rats |
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| Kong Xiangying,Bian Xiuwu,Ren Rongna,Bai Jiasi.Effects of zinc on the ultrastructure of hippocampus in developing rats[J].Acta Academiae Medicinae Militaris Tertiae,1996,18(4):340-343. |
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| Authors: | Kong Xiangying Bian Xiuwu Ren Rongna Bai Jiasi |
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| Abstract: | The ultrastructure of the CA 3 region of the hippocampus was observed with electron microscopy in zinc deficient (ZD) and zinc excessive (ZE) rats from their breast feeding stage and onward. The findings were as follows: (1)The number of synaptic vesicles of the pyramidal cells was decreased in ZD rats. (2)Various degrees of degeneration of the neurons, glial cells and synapses and rupture of synaptic vesicles were seen in ZE animals. These findings suggest that the changes of hippocampal ultrastructures might be one of the fundamental mechanisms of the changes of the learning and memory capacity in ZD and ZE rats. |
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| Keywords: | zinc deficiency zinc excess hippocampus ultrastructure rat |
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